Knowledge Management Software :: essays research papers

I will attempt to inform you on what Knowledge Management Software (KMS) is. I will also attempt to give you a brief history and specific benefits the KMS adds to our specific global organization. First let’s talk about knowledge management (KM), and define what it is? I had the opportunity to talk with three coworkers and for them to give me a definition that I myself had no idea about until I decided to do some research. Well, my first interview went with Tasha who’s a Supply person. She had no idea; she thought it could not be such a thing as KM. Secondly, I interviewed Michelle our unit secretary. She said she’d heard of it but couldn’t possibly tell me what it meant. And lastly, I interviewed Tonya, our personnel specialist. Tonya said she knew what knowledge was. According to her, knowledge had something to do with knowing information and management according to her is knowing what to do with the information. Well, that gave me a starting point. Well, what is knowledge? Let’s see, knowledge has two basic definitions of interest. The first pertains to a defined body of information. Depending on the definition, the body of information might consist of facts, opinions, ideas, theories, principles, and models (or other frameworks). Clearly, other categories are possible, too. Subject matter (e.g., chemistry, mathematics, etc.) is just one possibility. In addition, knowledge also refers to a person’s state of being with respect to some body of information. These states include ignorance, awareness, familiarity, understanding, facility, and so on. Now that was a mouthful. Management on the other had has some of the similarities as Tonya mention above. When I researched the definition for management it means to manage or be responsible for controlling or organizing someone or something especially a business. After reviewing both and putting those together KM means - the processes of finding, collecting and sharing information within an organization. This has taken the business community by storm in the last five years. It is about making optimum use of the intellectual capital (skills, ideas and knowledge) of employees. The history of KMS has many faces. With continuously emerging work roles, the unlocking of an enterprise's information to members at every level has become essential to ensure that each has the knowledge, skills and authority to be productive. These new work roles demand that every individual have access to the correct data and knowledge in order to make their own effective business decisions.

It’s up in the Air, or Is It Essay

The article elaborates on how individual sociological imagination can connect social structure to life history. In this case, sociological imagination refers to understanding of individual behavior as the product of historical processes that affects a person’s social environment. The rules of social structure are considered to restrict the conduct of individuals and also mould outcomes for them. However, students are not able to see the connection between individual action and structural outcomes. In sociological imagination, social structural explanation can be used to answer the several questions of social stratification. It is evident that other forces than individual characteristics shape the outcome and distributions of societal rewards (Renzulli, Aldrich, Reynolds, 51). Organizations help to reduce inequality in the society by allowing prospective entrepreneurs from different social origins to access to wealth-generating assets. In order to show how social structure of society shapes the results for individuals, the students can be engaged in a multiple rounds of coin tossing game. The game will also include some rules and regulations to be followed. The results of the game will be highly predictive on how the social structures mould the outcomes of individuals. From the distribution of the coins, the students will realize that inequality and personal prosperity are not the result of personal characteristics (Renzulli, Aldrich, & Reynolds, 56). The alteration of the rules of the game will help the students to see how real world processes generate inequality in the community. It is clearly acknowledged that, structures and rules affect a person’s ability to access an opportunity regardless of his or her talent. However, some improvements have to be done on the game in order to give the best results to the students. Therefore, coin tossing game can be used to effectively demonstrate how sociological imagination increase student understanding of the social world.

Cell And Breast Cancers And Colorectal Cancer - 1161 Words

An antimetabolite, 5FU is a pyrimidine analog that irreversibly inhibits TS. Thymidine is a nucleoside and a major component of the DNA and is hence required by cells for proliferation. Deoxyuridine monophostate (dUMP) upon methylation by TS generates thymidine monophostate (dTMP). 5FU interrupts the activity of TS and creates a shortage in the levels of dTMP. Thus the rapidly proliferating cells undergo death due to lack of thymidine nucleoside. The drug has successful applications in colorectal and breast cancers and is used in various combination therapies with methotrexate (Maddur et al., 2009). The concentration used for the experiments is 10  µM Oxaliplatin is an antineoplastic platinum drug. Platinum drugs target DNA synthesis by†¦show more content†¦215 cells have high proliferating rates as compared to 253 cells. To generate metformin resistant cells, 215 and 253 were cultured 4-8 weeks in the presence of 3mM of metformin. Cells were considered resistant after 3 serial passages in vitro. For the generation and enrichment of cancer stem cells, PDAC cells at 106 cells/ml concentration were grown in a serum free Dulbecco’s Modified Eagle’s Medium (DMEM-F12) complemented with B-27 and FGF. The cells were seeded in ultra-low attachment flasks. This aids in the development and the expansion of the PDAC spheres (cancer stem cells). Metformin was added (at 1:1000 dilution) in case of culturing metformin resistant spheres. All the cells were contained in a T-75 flask and incubated at 37 °C. The regular cancer cells were seeded at 106 cells/ml concentration in RPMI containing 10% (v/v) FBS. The cells were cultured in regular attachment T-75 flasks. Metformin at 1:1000 dilutions was added in case of culturing metformin resistant PDAC cells. After incubating for 7 days, spheres increase in size and range from 40-120  µm. For serial passaging, spheres were harvested using 40  µm cell strainers (filters), trypsinised to dissociate into single cells and then grown again for 4 days in the same conditions. Growth media was aspirated and the flask was washed with PBS. The cells were trypsinised and kept in an incubator at 37 °C until the cells